How DataCore Analytics Keeps Data Confidential
12 May 2026
Single-cell data is easy to generate and easy to over-interpret. We do the quality control properly, annotate cells against reference atlases, and tell you which clusters are real.
Single-cell experiments are expensive, and the analysis decisions made in the first week determine what the data can show. Filtering thresholds, integration method and clustering resolution are all judgement calls, and the wrong ones produce clusters that do not exist.
We document every one of those decisions and show you the effect of the alternatives, so the clusters in your paper are ones you can defend.
Each project uses the subset of these that your research question requires.
Empty droplet detection, ambient RNA correction, doublet identification, and filtering on genes per cell, counts and mitochondrial fraction — with the thresholds justified rather than copied from a tutorial.
Merging samples, donors or timepoints using Harmony, Seurat CCA/RPCA or scVI, with quantitative assessment of whether biological signal survived the correction.
Dimensionality reduction, graph-based clustering across a range of resolutions, and annotation using both marker-based and reference-based methods (SingleR, Azimuth, CellTypist) against relevant atlases.
Pseudobulk differential expression between conditions within each cell type — the statistically correct approach — plus cell proportion testing across groups.
Pseudotime and RNA velocity where the biology supports it, and ligand-receptor interaction analysis with CellChat or CellPhoneDB.
Typical turnaround: 3–6 weeks depending on sample number and integration complexity
Indicative price: From $1,200 for a single sample through to annotation
Reduced rates are available for students and researchers at African public institutions. Every project is quoted in writing before work begins.
Services are provided for research purposes only. They are not intended for clinical diagnosis, treatment decisions or individual health assessment. See how it works, data submission guidelines and what you receive.
Bioinformatics, biostatistics and data science support for research teams across Africa.
12 May 2026
28 April 2026